Cell-preservation technique could make CAR-T cell therapy more accessible

Researchers at MIT have developed a new method to preserve CAR-T cells, which are engineered immune cells used to treat certain blood cancers. As MIT News tells it, the team replaced a harsh chemical preservative with nontoxic antifreeze sugars, allowing the cells to be thawed and injected without the complex processing steps currently required at most hospitals. In mouse models, this technique led to higher cell survival rates and better outcomes when treating glioblastoma and lymphoma. The researchers now aim to work with hospitals to see if the process can be integrated into clinical production.

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