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Researchers discover why fructose doesn't satisfy hunger like glucose

health

According to ScienceDaily, new research reveals that your brain treats fructose and glucose very differently—even though they look identical on a nutrition label. Scientists tested this in mice, measuring brain activity in cells that regulate hunger. When the animals consumed glucose, it strongly suppressed those appetite signals. Fructose, by contrast, had a much weaker effect—the mice stayed hungrier. Even more revealing: high-fructose corn syrup triggered the strongest response, and the mice preferred it to other sugars. The takeaway is striking. It's not just how many calories you consume, but what type of sugar. Fructose may leave you feeling hungry even after consuming the same caloric intake as glucose. This distinction could help explain why high-fructose sweeteners—ubiquitous in processed foods and soft drinks—may drive overeating and obesity more than other sugars. Your calorie label doesn't distinguish. But apparently, your brain does.

Source: https://www.sciencedaily.com/releases/2026/06/260623083106.htm

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