The mystery behind what killed Botticelli’s muse: has a 550-year-old medical case been solved?

The Conversation reports that Simonetta Vespucci, the muse immortalized in Botticelli's Renaissance paintings, died suddenly at age twenty-three nearly five hundred fifty years ago, and her death has long remained unexplained. Her surviving portraits may now provide clues to solving this centuries-old medical mystery.

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