DNA repair enzymes favor specific sequences, shaping mutation patterns in the human genome

DNA repair enzymes show a preference for certain genetic sequences, a pattern that shapes how mutations accumulate in the human genome. Mutations result when damaged DNA isn't properly repaired, and understanding these repair preferences could help explain why some genetic changes lead to disease and aging, while others drive evolution by creating genetic variation. Phys.org reports that scientists still don't fully understand what determines whether a particular stretch of damaged DNA will be successfully repaired.

Listen to this story

Hear this and more stories in a personalized audio briefing.

Open The Chonkerton